KEGG   Homo sapiens (human): 5596
Entry
5596              CDS       T01001                                 
Symbol
MAPK4, ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
Name
(RefSeq) mitogen-activated protein kinase 4
  KO
K06855  mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04657  IL-17 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    5596 (MAPK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5596 (MAPK4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     5596 (MAPK4)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   5596 (MAPK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1
Other DBs
NCBI-GeneID: 5596
NCBI-ProteinID: NP_002738
OMIM: 176949
HGNC: 6878
Ensembl: ENSG00000141639
UniProt: P31152
Position
18:50559612..50731826
AA seq 587 aa
MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
NT seq 1764 nt   +upstreamnt  +downstreamnt
atggctgagaagggtgactgcatcgccagtgtctatgggtatgacctcggtgggcgcttt
gttgacttccaacccctgggcttcggtgtcaatggtttggtgctgtcggccgtggacagc
cgggcctgccggaaggtcgctgtgaagaagattgccctgagcgatgcccgcagcatgaag
cacgcgctccgagagatcaagatcattcggcgcctggaccacgacaacatcgtcaaagtg
tacgaggtgctcggtcccaagggcactgacctgcagggtgagctgttcaagttcagcgtg
gcgtacatcgtccaggagtacatggagaccgacctggcacgcctgctggagcagggcacg
ctggcagaagagcatgccaagctgttcatgtaccagctgctccgcgggctcaagtacatc
cactccgccaacgtgctgcacagggacctgaagcccgccaacatcttcatcagcacagag
gacctcgtgctcaagattggggatttcgggttggcaaggatcgttgatcagcattactcc
cacaagggttatctgtcagaagggttggtaacaaagtggtaccgttccccacgactgctc
ctttcccccaataactacaccaaagccatcgacatgtgggccgccggctgcatcctggct
gagatgcttacggggagaatgctctttgctggggcccatgagctggagcagatgcaactc
atcctggagaccatccctgtaatccgggaggaagacaaggacgagctgctcagggtgatg
ccttcctttgtcagcagcacctgggaggtgaagaggcctctgcgcaagctgctccctgaa
gtgaacagtgaagccatcgactttctggagaagatcctgacctttaaccccatggatcgc
ctaacagctgagatggggctgcaacacccctacatgagcccatactcgtgccctgaggac
gagcccacctcacaacaccccttccgcattgaggatgagatcgacgacatcgtgctgatg
gccgctaaccagagccagctgtccaactgggacacgtgcagttccaggtaccctgtgagc
ctgtcgtcggacctggagtggcggcctgaccggtgccaggacgccagcgaggtacagcgc
gacccgcgcgcgggttcggcgccactggctgaggacgtgcaggtggacccgcgcaaggac
tcgcacagcagctccgagcgcttcctagagcagtcgcactcgtccatggagcgcgccttc
gaggccgactacgggcgctcctgcgactacaaggtggggtcgccgtcctacctggacaag
ctgctgtggcgcgacaacaagccgcaccactactcggagcccaagctcatcctggacctg
tcgcactggaagcaggcggccggcgcgccccccacggccacggggctggcggacacgggg
gcgcgcgaggacgagccggccagcctcttcctggagatcgcgcagtgggtcaagagcacg
cagggcggcccagagcacgccagcccgcccgccgacgaccccgagcgccgcttgtctgcc
tcgccccccggccgcccggccccggtggacggcggcgccagcccccagttcgacctggac
gtgttcatctcccgcgccctgaagctctgcaccaagcccgaggacctgccggacaataaa
ctgggcgacctcaatggtgcgtgcatccccgagcaccctggcgacctcgtgcagaccgag
gccttctccaaagaaaggtggtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (41)   
   RefSeq(nuc) (19)   
   GenBank (11)   
   EMBL (11)   
Protein domain (4)   
   Pfam (4)   
All databases (82)   

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